When we discovered multiple clinical studies reporting 70%-90% of debris released during stenting was <100 microns1-5, meaning it was capable of passing through the large pores of traditional distal filters, we knew there had to be a better way.

So, we created one.

 

Our CAS-IEP technology is setting a new standard in carotid stenting.

Paladin® IEP System
2-in-1: balloon + filter

Neuroguard IEP® System
3-in-1: stent + balloon + filter

Integrated Embolic Protection (IEP) platform. Captures emboli other protection mechanisms can’t.6

  • Designed to safeguard against stroke & cognitive impairment associated with microembolization7-9
  • Proprietary 40 micron filter pores are 3-4x smaller than traditional filters and mesh-covered stents6
  • Physician-controlled filter is adjusted to the anatomy to help prevent particles from passing around the filter

The difference between success and stroke is measured in microns

Designed for Precision: Built for precise and predictable stent deployment10 and vessel conformability

Built to Fit: Short landing zone means the system can be used on more than 94% of patient anatomies10

More Efficiency: 3-in-1 system reduces catheter exchanges and improves procedural efficiency10

Contego’s FlexRingTM technology provides the best of both open and closed cell stents with optimized flexibility AND radial strength.10

Let’s Get to ZeroTM

Clinical studies of IEP technology in CAS procedures have consistently shown unprecedented 99% freedom from strokes.1,2,11

The Neuroguard IEP System is approved for sale in the USA. Caution: Federal (United States) law restricts this device to sale by or on order of a physician. Prior to use, please see the Instructions for Use for a complete listing of Indications, Contraindications, Warnings, Precautions, Potential Adverse Events, Operator Instructions, and Directions for Use.

References

  1. Langhoff R, et al. Catheter Cardiovasc Interv. 2022;100(6):1090-1099.
  2. Langhoff R, et al. JACC Cardiovasc Interv. 2019;12:395-403.
  3. Petkoska D, et al. Cardiovasc Revasc Med. 2024;63:43-51.
  4. Henry M, et al. Catheter Cardiovasc Interv. 2007 Jun 1;69(7):1026-35.
  5. Ledwoch J, et al. Int J Cardiol. 2017 Jan 15;227:550-555.
  6. Per IFUs of devices: Pore sizes of various embolic protection devices: Angioguard 100µm, NAV6 120µm, and mesh-covered stents: CGuard 165µm, Terumo 375µm, Gore 500µm.
  7. Zhou W, et al. Jour of Vasc Surg. 2017 Mar;65(3):686-694.
  8. Hitchner E, et al. Jour of Vasc Surg. 2016 Dec;64(6):1719-1725.
  9. Maggio P, et al. Jour of Neuro Sciences. 2013 May 15;328(1-2):58-63.
  10. Data on File. Contego Medical, Inc.
  11. Gray W, MD. A Multicenter Trial Evaluation of the Neuroguard Carotid Artery Stent System With Integrated Embolic Protection: 30-Day and 1-year Outcomes of PERFORMANCE II. Presented at: VIVA; November 1 2023; Las Vegas, NV.
  12. EVA-3S: Mas, Jean-Louis, et al. N Engl J Med 2006;355:1660-71.
  13. CREST: Brott et al, N Engl J Med 2010;363:11-23.
  14. SAPPHIRE Randomized: Yadav JS, et al. N Engl J Med 2004;351:1493-501.
  15. ACT 1: N Engl J Med 2016;374:1011-20.
  16. Kwolek, CJ et al. J Vasc Surg. 2015 Nov;62(5):1227-34.